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- Urticaria & allergic reactions
Urticaria & allergic reactions
Hives without airway or circulation problems — and when it’s anaphylaxis.
Typical consult⏱ 15 min
Investigations🔬 Usually none
Usual outcome💊 Non-sedating antihistamine ± short steroid
0–5Red flags + history5–12Examine12–17Decide17–24Treat + explain24–30Safety-net + document
1Rule out first — red flags
| If you find… | …then |
|---|---|
| Airway, breathing or circulation problem | Anaphylaxis — IM adrenaline 500 micrograms now |
| Angioedema of tongue / throat, hoarseness, stridor | Airway — ED / anaesthetics |
| On an ACE inhibitor with angioedema (no hives) | ACEi angioedema — doesn’t respond to adrenaline as well; stop ACEi, ED |
| Hives with fever, joint pain, bruising, lasting > 48 h in one spot | Urticarial vasculitis / systemic illness |
2Focused history
3Focused examination
4Decide — investigate only if it changes the plan
| Investigation | Only if… |
|---|---|
| None for acute urticaria | Tests rarely help; refer if recurrent / chronic (> 6 weeks) |
5Treat & send home
Management & advice
- Avoid the trigger if identified; stop suspected drugs
- Cool showers, loose clothing
- If anaphylaxis occurred: observe per RCUK, allergy referral, 2 adrenaline auto-injectors
Refer / follow-up
- Anaphylaxis or severe angioedema → ED then allergy clinic
- Chronic urticaria > 6 weeks → GP / dermatology
℞
Discharge prescription (TTO)Typical adult doses — check the BNF/BNFc, allergies, renal function, pregnancy and interactions.
| Drug | Dose | Duration / notes |
|---|---|---|
| Cetirizine (or loratadine) | 10 mg once a day | Until symptoms settle (up to 6 weeks) |
| Fexofenadine (alternative) | 180 mg once a day | As above |
| Prednisolone (severe acute urticaria only) | 40 mg once a day | Up to 7 days |
6Safety-net
Say it like this
This is hives, an allergic-type rash. It isn’t dangerous on its own, and the antihistamine once a day should control it. It can come and go for a few days. If your lips, tongue or throat swell, you find it hard to breathe or swallow, or you feel faint, call 999 straight away.
Come back / call 111 — or 999 if severe — if:
- Swelling of the lips, tongue or throat, difficulty breathing or swallowing, feeling faint — call 999
- Rash with fever or feeling very unwell
- Not settling after 2 weeks
7Patient leaflets — scan & go
Official NHS pages. Ask the patient to scan the code with their phone camera, or tap “Show to patient” to make it full screen.
8Document
Urticaria & allergic reactions — clinic note
A structure to document efficiently. It is not a completeness check — use your trust’s system and your clinical judgement.
URGENT CARE — URTICARIA & ALLERGIC REACTIONS
PRESENTING COMPLAINT:
HISTORY
Onset, trigger (food, drug, sting, infection, exercise):
Swelling of lips/tongue, breathing, dizziness:
New medicines (NSAIDs, antibiotics, ACE inhibitors):
Previous episodes, atopy:
RED FLAGS (record present / absent)
[ ] Airway, breathing or circulation problem
[ ] Angioedema of tongue / throat, hoarseness, stridor
[ ] On an ACE inhibitor with angioedema (no hives)
[ ] Hives with fever, joint pain, bruising, lasting > 48 h in one spot
PMH:
DRUG HISTORY:
ALLERGIES:
SOCIAL (job / who is at home / driving):
OBSERVATIONS: RR SpO2 HR BP Temp (NEWS2 )
EXAMINATION
Obs incl. BP and sats:
Airway: voice, stridor, tongue/uvula swelling:
Wheals: transient, blanching, itchy; angioedema:
INVESTIGATIONS: none required / None for acute urticaria — result:
IMPRESSION:
PLAN
Treatment / TTO (drug, dose, duration):
Advice given:
Leaflet given (QR / printed): Hives
Follow-up / referral:
SAFETY-NETTING (told to return / call 111 / 999 if):
- Swelling of the lips, tongue or throat, difficulty breathing or swallowing, feeling faint — call 999
- Rash with fever or feeling very unwell
- Not settling after 2 weeks
Patient understands and agrees with the plan: Y / N
Seen by: Grade: Date/Time:
✓Guidelines
Doses are typical adult doses drawn from the guidance above. Always check the current BNF/BNFc and your local antimicrobial policy.
More wounds, burns & skin
Lacerations & wound careClose it right, check tetanus, and know which wounds aren’t yours.Minor burns & scaldsCool, cover, size it — and know when it goes to the burns unit.Human & animal bitesWho gets prophylaxis, rabies risk and the fight bite.Insect bites, stings & tick bitesBig local reactions vs infection vs anaphylaxis — and Lyme.