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Compartment syndrome

Pain out of proportion is the warning — pulselessness is far too late. Suspect it early in anyone at risk with escalating pain, act immediately by removing everything constrictive, and get an urgent orthopaedic decision. Fasciotomy saves the limb; waiting for "classic" signs loses it. Built for revision, not live patient decisions.

1

Settle them, and check the basics

minutes matter

Red flags — what each should make you think

Pain out of proportion to the injurycompartment syndrome Increasing analgesia requirementcompartment syndrome Pain on passive stretchcompartment syndrome Tense, swollen compartmentcompartment syndrome Paraesthesia, weaknesslate — act now Unconscious / sedated / regional blockcan't report pain — monitor pressures
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Pearl

Pulses are usually present in compartment syndrome. Compartment pressure rises above capillary pressure long before it reaches arterial pressure, so a palpable pulse never excludes it. The "5 Ps" describe a limb that is already dying.

Immediate actions (BOAST)

  • ✂Split everything to skin
  • ↑Position and re-evaluate
  • BPMaintain normotension
  • O₂Oxygen
  • ☎Urgent orthopaedic review
  • 🔪Fasciotomy
2

Understand the patient

who · how to assess

Who is at risk?

  • Tibial shaft fractures (the commonest), forearm fractures, supracondylar fractures in children
  • Crush injuries, prolonged lie / immobilisation, reperfusion after vascular repair
  • Tight casts or dressings, burns (circumferential)
  • IV/IO extravasation, drug injection, anticoagulation, bleeding disorders
  • Young men with large muscle mass

Assessing it

  • Pain out of proportion, escalating, poorly relieved by analgesia
  • Pain on passive stretch of the muscles in the compartment (e.g. toe flexion/extension for the leg)
  • Tense, "woody" compartment
  • Late: paraesthesia, paralysis, pallor, pulselessness

Compartment pressure monitoring helps when clinical assessment is unreliable (unconscious, sedated, nerve block, children). A difference between diastolic BP and compartment pressure (ΔP) below 30 mmHg, or an absolute compartment pressure above 40 mmHg, should prompt consideration of urgent decompression (BOAST).

Work A–E — assess and act as you go

AAirway. ——
BBreathing. —oxygen if needed
CCirculation. BP (hypotension worsens perfusion), pulses (usually present).keep normotensive
DDisability. Pain score trend, sensation, power distal to the compartment.document hourly
EExposure. Remove all dressings to skin and look at the whole limb; check other limbs if crush.split casts
3

The diagnoses you must not miss

tap to open each

What points toward it, what would rule it in, and how to manage it.

4

Investigate — what to order, when, and what it tells you

test with a question in mind

Clinical

Main tool
Serial documented examination — pain, stretch, compartments, neurology.

Compartment pressure

When
Unreliable examination or equivocal signs.
Threshold
ΔP (diastolic − compartment) below 30 mmHg, or absolute pressure above 40 mmHg.

Bloods

Check
CK, U&E, K⁺, clotting.

Don't delay for tests

Compartment syndrome is a clinical diagnosis. If the clinical picture fits, the treatment is fasciotomy; no imaging can make or exclude the diagnosis.

5

How the plan comes together

disposition · handover

theatre

Diagnosed: immediate fasciotomy. Inconclusive: hourly documented examination, consider pressure monitoring, senior decision-maker review.

Hand over: time of symptom onset, findings, pressures if measured, time decision made.

close observation

At-risk limb without signs: hourly neurovascular and pain observations documented, low threshold to review, clear escalation plan.

🩺
Pearl

If the pain is out of proportion, think compartment syndrome. Split everything to skin, keep the limb level, and call a senior now. A palpable pulse doesn't exclude it. Nicely done getting here.

✎

Clerking template

copy or download

Compartment syndrome — documentation structure

A structure and prompt list to help you document and think systematically. It is not a completeness check and cannot guarantee nothing is missed — use your trust's own proforma, your seniors, and your clinical judgement.

COMPARTMENT SYNDROME — CLERKING TEMPLATE PRESENTING COMPLAINT: HISTORY OF PRESENTING COMPLAINT Injury / mechanism / time: Cast / dressing applied (time): Pain trend / analgesia requirement: Anticoagulants / bleeding disorder: Able to report pain reliably? Y / N RED FLAGS ASKED (record present or absent) [ ] Pain out of proportion to the injury -> compartment syndrome [ ] Increasing analgesia requirement -> compartment syndrome [ ] Pain on passive stretch -> compartment syndrome [ ] Tense, swollen compartment -> compartment syndrome [ ] Paraesthesia, weakness -> late — act now [ ] Unconscious / sedated / regional block -> can't report pain — monitor pressures SCORES / KEY CHECKS Pain out of proportion: Y / N Pain on passive stretch: Y / N Compartments tense (which): Sensation / power distal: Pulses: Compartment pressure (if measured): Diastolic BP: Delta-P: Dressings split to skin (time): Ortho senior informed (time): PAST MEDICAL HISTORY: DRUG HISTORY: ALLERGIES: SOCIAL HISTORY (smoking / alcohol / function / who's at home): FAMILY HISTORY: OBSERVATIONS: RR SpO2 ( % O2) HR BP Temp GCS NEWS2 EXAMINATION A - B - C - D - (GCS pupils glucose ) E - INVESTIGATIONS ORDERED: IMPRESSION: DIFFERENTIALS CONSIDERED: [ ] Acute compartment syndrome [ ] Rhabdomyolysis / reperfusion [ ] Arterial injury (mimic) [ ] Pain from fracture alone [ ] DVT [ ] Cellulitis PLAN: 1. 2. 3. ESCALATION / SENIOR DISCUSSION: Discussed with: Time: Advice: SAFETY NET / IF DETERIORATES: Documented by: Grade: Date/Time:
?

Test yourself

active recall

Cover the answer, say it out loud, then reveal. Retrieval beats re-reading.

0 / 9 known
Red flag
Pain out of proportion to the injury — what should it make you think?
compartment syndrome
Red flag
Increasing analgesia requirement — what should it make you think?
compartment syndrome
Red flag
Pain on passive stretch — what should it make you think?
compartment syndrome
Red flag
Tense, swollen compartment — what should it make you think?
compartment syndrome
Red flag
Paraesthesia, weakness — what should it make you think?
late — act now
Red flag
Unconscious / sedated / regional block — what should it make you think?
can't report pain — monitor pressures
Must not miss
How do you rule in acute compartment syndrome?
Clinical diagnosis; compartment pressures if unreliable exam.
Must not miss
How do you rule in rhabdomyolysis / reperfusion?
CK, U&E, K⁺, urine dip.
Must not miss
How do you rule in arterial injury (mimic)?
ABPI, CT angiogram.
Q

Frequently asked questions

quick answers
What are the red flags for compartment syndrome?
  • Pain out of proportion to the injury — think compartment syndrome
  • Increasing analgesia requirement — think compartment syndrome
  • Pain on passive stretch — think compartment syndrome
  • Tense, swollen compartment — think compartment syndrome
  • Paraesthesia, weakness — think late — act now
  • Unconscious / sedated / regional block — think can't report pain — monitor pressures
What is the initial management of compartment syndrome?
  • Split everything to skin — bandages, padding and casts along their full length
  • Position and re-evaluate — BOAST: limb elevated and re-evaluated within 30 minutes; avoid excessive elevation — follow local guidance
  • Maintain normotension — treat hypotension
  • Oxygen — if hypoxic
  • Urgent orthopaedic review — senior decision
  • Fasciotomy — immediate surgical decompression once diagnosed (consultant decision)

Always alongside senior support and your local guideline.

What diagnoses must you not miss in compartment syndrome?
  • Acute compartment syndrome — fasciotomy
  • Rhabdomyolysis / reperfusion — crush · long lie
  • Arterial injury (mimic) — pulseless, cold

Open each one in the must-not-miss section for what points toward it, how to rule it in, and how to manage it.

What investigations should a junior doctor order for compartment syndrome?
  • Clinical — Serial documented examination — pain, stretch, compartments, neurology.
  • Compartment pressure — ΔP (diastolic − compartment) below 30 mmHg, or absolute pressure above 40 mmHg.
  • Bloods — CK, U&E, K⁺, clotting.
Admit or discharge: how is the plan decided for compartment syndrome?
  • Theatre — Diagnosed: immediate fasciotomy. Inconclusive: hourly documented examination, consider pressure monitoring, senior decision-maker review.
  • Close observation — At-risk limb without signs: hourly neurovascular and pain observations documented, low threshold to review, clear escalation plan.
Is there a clerking template for compartment syndrome?

Yes — there is a free clerking template for compartment syndrome on this page, structured as presenting complaint, red flags asked, history, examination (A–E), investigations, differentials, plan and escalation. You can copy it or download it as a Word document. Jump to the template.

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