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Atrial fibrillation
Three questions: is it unstable, how long has it been there, and does the patient need anticoagulation? Cardiovert the unstable patient, treat the cause of fast AF (sepsis, dehydration, thyrotoxicosis), choose rate or rhythm control based on how long it has been present, and assess stroke and bleeding risk. Built for revision, not live patient decisions.
Settle them, and check the basics
stable or unstable?Red flags — what each should make you think
Fast AF is often a symptom, not the disease. A septic, dehydrated patient in AF at 150 needs fluids and antibiotics, not a beta-blocker. Treat the trigger and the rate often settles on its own.
First actions
- ECG12-lead ECG
- ⚡Unstable → electrical cardioversion
- 🔍Look for a trigger
- ⏱Establish the onset
- HepAnticoagulate
- K/MgCorrect electrolytes
Understand the patient — rate, rhythm, anticoagulation
NICE NG196Rate or rhythm?
- Onset clearly under 48 h — rate or rhythm control; rhythm options are electrical cardioversion or pharmacological (flecainide if no structural heart disease, or amiodarone if structural heart disease). Anticoagulate with heparin while deciding.
- Onset over 48 h or unknown — rate control. Cardioversion only after at least 3 weeks of therapeutic anticoagulation (or TOE-guided).
- Rate control drugs — beta-blocker (not sotalol) or rate-limiting CCB (diltiazem, verapamil — avoid in heart failure with reduced EF). Digoxin for sedentary patients or with heart failure. Amiodarone may be used in the acute setting with heart failure.
Stroke and bleeding risk
- CHA₂DS₂-VASc — CHF, Hypertension, Age ≥75 (2), Diabetes, Stroke/TIA/thromboembolism (2), Vascular disease, Age 65–74, Sex (female)
- NICE: offer anticoagulation (a DOAC first-line) with a score of 2 or more; consider it for men with a score of 1
- ORBIT to assess bleeding risk — address modifiable risks (BP, alcohol, NSAIDs) rather than withholding anticoagulation
- Don't use aspirin alone for stroke prevention in AF
Work A–E — assess and act as you go
The diagnoses you must not miss
tap to open eachWhat points toward it, what would rule it in, and how to manage it.
AF with hypotension, syncope, chest pain/ischaemia or acute heart failure.
Clinical + ECG.
Emergency synchronised DC cardioversion (sedation/GA); amiodarone if it fails or recurs. Don't delay for anticoagulation.
Very fast, irregular, broad bizarre complexes of varying width.
ECG; expert review.
No AV-node blockers. Cardioversion or expert-guided drugs.
New focal neurology; a cold, painful, pulseless limb; abdominal pain out of proportion (mesenteric ischaemia).
CT head / CT angiogram.
Stroke pathway (thrombolysis/thrombectomy decisions), vascular surgery for limb ischaemia, surgical review for mesenteric ischaemia.
Fever, infection source, weight loss, tremor, goitre.
TFT, CRP, cultures, lactate.
Treat the cause; beta-blockers help thyroid-driven AF (with endocrine input). Avoid rate control in compensatory tachycardia.
Investigate — what to order, when, and what it tells you
test with a question in mindECG
Bloods
Imaging
How the plan comes together
disposition · handoverhome
Stable, rate controlled (resting HR under 110), trigger dealt with, anticoagulation decided and started, follow-up arranged (GP/AF clinic).
admit
Unstable, uncontrolled rate, heart failure, significant trigger (sepsis), new stroke, or pre-excitation.
Hand over: onset time, rate/rhythm strategy, anticoagulation, CHA₂DS₂-VASc and ORBIT.
Unstable means shock. Stable means find the trigger, decide rate or rhythm by the 48-hour rule, and never forget the stroke risk. Nicely done getting here.
Clerking template
copy or downloadAtrial fibrillation — documentation structure
A structure and prompt list to help you document and think systematically. It is not a completeness check and cannot guarantee nothing is missed — use your trust's own proforma, your seniors, and your clinical judgement.
Test yourself
active recallCover the answer, say it out loud, then reveal. Retrieval beats re-reading.
0 / 10 knownFrequently asked questions
quick answersWhat are the red flags for fast atrial fibrillation (AF)?
- Shock, syncope, ischaemia, HF — think unstable — DC cardioversion
- Irregular, broad, very fast — think pre-excited AF — no AV blockers
- Fever, sepsis, dehydration — think secondary AF — treat cause
- Tremor, weight loss, goitre — think thyrotoxicosis
- Sudden cold pale limb — think acute limb ischaemia
- New neuro deficit — think embolic stroke
What is the initial management of fast atrial fibrillation (AF)?
- 12-lead ECG — confirm AF, look for ischaemia, pre-excitation, QRS width
- Unstable → electrical cardioversion — emergency synchronised DC cardioversion without delaying for anticoagulation
- Look for a trigger — sepsis, hypovolaemia, PE, thyroid, alcohol, electrolytes, ischaemia
- Establish the onset — under 48 h vs over 48 h or unknown
- Anticoagulate — start heparin or a DOAC if cardioversion is planned (unless contraindicated)
- Correct electrolytes — K⁺ and Mg²⁺
Always alongside senior support and your local guideline.
What diagnoses must you not miss in fast atrial fibrillation (AF)?
- Unstable AF — shock · ischaemia · HF
- Pre-excited AF — WPW
- Embolic complications — stroke · limb · gut
- Thyrotoxicosis / sepsis-driven AF — treat the trigger
Open each one in the must-not-miss section for what points toward it, how to rule it in, and how to manage it.
What investigations should a junior doctor order for fast atrial fibrillation (AF)?
- ECG — AF, rate, pre-excitation, ischaemia, LVH.
- Bloods — U&E, K, Mg, TFT, FBC, CRP, glucose, clotting (before anticoagulation).
- Imaging — Heart failure, infection.
Admit or discharge: how is the plan decided for fast atrial fibrillation (AF)?
- Home — Stable, rate controlled (resting HR under 110), trigger dealt with, anticoagulation decided and started, follow-up arranged (GP/AF clinic).
- Admit — Unstable, uncontrolled rate, heart failure, significant trigger (sepsis), new stroke, or pre-excitation.
Is there a clerking template for fast atrial fibrillation (AF)?
Yes — there is a free clerking template for fast atrial fibrillation (AF) on this page, structured as presenting complaint, red flags asked, history, examination (A–E), investigations, differentials, plan and escalation. You can copy it or download it as a Word document. Jump to the template.
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